Friday, 5 May 2023

ANESTHESIOLOGISTS

 


ANESTHESIOLOGIST


An anesthesiologist is a medical doctor who specializes in administering anesthesia to patients before, during, and after surgical procedures. Anesthesia is a state of temporary unconsciousness or loss of sensation that allows a patient to undergo surgery or other medical procedures without feeling pain or discomfort. Anesthesiologists are also responsible for monitoring the patient's vital signs during the procedure and adjusting the anesthesia as needed to ensure the patient's safety and comfort.


Anesthesiologists work closely with other members of the surgical team, including surgeons, nurses, and surgical technicians. They also play a critical role in the management of pain after surgery and in the treatment of patients with chronic pain conditions.


Types:


There are several types of anesthesia that anesthesiologists may use to achieve the desired level of unconsciousness or pain relief for a patient during a surgical procedure. Some of the most common types of anesthesia include:


1. General anesthesia: This is a state of complete unconsciousness that is achieved through the use of intravenous medications and inhalational agents. General anesthesia is typically used for more complex surgeries or procedures.


2. Regional anesthesia: This involves numbing a specific region of the body, such as an arm or a leg, using a local anesthetic. Regional anesthesia is often used for procedures in which the patient needs to remain conscious or for patients who are not good candidates for general anesthesia.


3. Local anesthesia: This involves numbing a small area of the body using a local anesthetic. Local anesthesia is commonly used for minor procedures, such as dental work or minor skin surgeries.


4. Sedation: This involves giving the patient medications to help them relax and feel drowsy during a procedure without being fully unconscious. Sedation is often used for minor procedures such as colonoscopies or endoscopies.


Anesthesiologists may also use a combination of these different types of anesthesia, depending on the specific needs of the patient and the type of surgery or procedure being performed.


Roles:


Anesthesiologists play several important roles in the surgical process, including:


1. Pre-operative assessment: Before a surgical procedure, the anesthesiologist will meet with the patient to assess their medical history, current health status, and any medications or allergies they may have. This helps the anesthesiologist determine the most appropriate type and dosage of anesthesia to use for the procedure.


2. Administration of anesthesia: During the surgical procedure, the anesthesiologist is responsible for administering the appropriate type and amount of anesthesia to the patient. They closely monitor the patient's vital signs, such as heart rate, blood pressure, and oxygen levels, and adjust the anesthesia as needed to ensure the patient's safety and comfort.


3. Pain management: Anesthesiologists also play a key role in managing pain after surgery, working with the patient to develop a plan for pain relief during the recovery process.


4. Emergency response: In the event of a medical emergency during surgery, the anesthesiologist is trained to respond quickly and effectively to stabilize the patient.


5. Patient safety: Anesthesiologists work closely with other members of the surgical team to ensure that the patient is safe and comfortable throughout the surgical process.


The role of the anesthesiologist is to ensure that the patient is safe and comfortable before, during, and after surgery, and to manage any complications that may arise during the procedure.

 

 

Thursday, 4 May 2023

Drug of Choice - ANTIMICROBIAL DRUGS


Drug of Choice - ANTIMICROBIAL DRUGS

▪️Drug of choice for gram negative sepsis - Piperacillin with Toberamycin

▪️Drug of choice for gram positive sepsis - Vancomycin with Gentamicin

▪️Drug of choice for toxic shock syndrome (Group A strep.) - Penicillin with Clindamycin

▪️Drug of choice for necrotizing fasciitis (Group A streptococcus) - Penicillin

▪️Drug of choice for prophylaxis of cardiac lesions in infective endocarditis - Amoxicillin

▪️Drug of choice for impetigo - Penicillin G

▪️Drug of choice for meningococcal meningitis - Penicillin G

▪️ Drug of choice for severe falciparum and chlorquinine resistant malaria - Quinine

▪️Drug of choice for enterococcus faecium - Linezolid

▪️Drug of choice for animal bite - Amoxicillin

▪️Drug of choice for otitis media - Amoxicillin

▪️Drug of choice for dirty wound prophylaxis - Cefazolin

▪️Drug of choice for pneumococcal pneumonia in adults - Amoxicillin

▪️Drug of choice for typhus fever - Chloramphenicol

▪️Drug of choice for lice infection - 1% permethrin

▪️Drug of choice for dental prophylaxis in infective endocarditis - Clarithromycin

▪️Drug of choice for cellulitis - Oxacillin

▪️Drug of choice for severe infection in penicillin allergic patient - Vancomycin

▪️Drug of choice for serious upper respiratory infections by atypical pathogens - Doxycycline

▪️Drug of choice for endocardial prophylaxis in patients allergic to penicillin - Vancomycin

▪️Drug of choice for histoplasmosis - Amphotericin B

▪️Drug of choice for invasive streptococcal infection - Clindamycin

▪️Drug of choice for dermatitis herpetiformis - Aspirin

▪️Drug of choice for cryptoccocus - Fluconazole

▪️Drug of choice for vulvovaginal candidiasis - Fluconazole

▪️Drug of choice for pyrazinamide induced hyperuricemia - Aspirin

▪️Drug of choice for systemic fungal infection - Amphotericin B

▪️Drug of choice for CMV retinitis - Gancyclovir

▪️Drug of choice for condyloma accuminata - Podophyline

▪️Drug of choice for cholera - Doxycycline

▪️Drug of choice for chlamydiae - Tetracycline (Eg: Doxycycline)

▪️Drug of choice for tropical sprue - Tetracycline

▪️Drug of choice for relapsing fever - Tetracycline

▪️Drug of choice for rocky spotted mountain fever - Tetracycline

▪️Drug of choice for tick typhus - Tetracycline

▪️Drug of choice for scrubs typhus - Tetracycline

▪️Drug of choice for syphilis - Penicillin G

▪️Drug of choice for toxoplasmosis - Cotrimoxazole

▪️Drug of choice for legionella - Azithromycin or Levofloxacin

▪️Drug of choice for lymphogranuloma venereum (LGV) - Azithromycin

▪️Drug of choice for kala-azar - Sodium Stibogluconate

▪️Oral drug of choice for kala-azar - Miltefosine

▪️Drug of choice for plague - Streptomycin

▪️Drug of choice for brucella - Streptomycin

▪️Drug of choice for tularemia - Streptomycin

▪️Drug of choice for rhinoscleroma - Streptomycin

▪️Drug of choice for actinomycosis - Penicillin-G

▪️Drug of choice for leprosy - Dapsone

▪️The most effective drug against Mycobacterium leprae - Rifampicin

▪️Drug of choice for microspora - Albendazole

▪️Drug of choice for serious upper urinary tract infections - Aminoglycosides

▪️Drug of choice for serious upper respiratory infections by atypical pathogens - Doxycycline

▪️Drug of choice for endocardial prophylaxis in patients allergic to penicillin - Vancomycin

▪️Drug of choice for histoplasmosis - Amphotericin B

▪️Drug of choice for invasive streptococcal infection - Clindamycin

▪️Drug of choice for dermatitis herpetiformis - Aspirin

▪️Drug of choice for cryptoccocus - Fluconazole

▪️Drug of choice for vulvovaginal candidiasis - Fluconazole

▪️Drug of choice for pyrazinamide induced hyperuricemia - Aspirin

▪️Drug of choice for systemic fungal infection - Amphotericin B

▪️Drug of choice for CMV retinitis - Gancyclovir

▪️Drug of choice for condyloma accuminata - Podophyline

▪️Drug of choice for cholera - Doxycycline

▪️Drug of choice for chlamydiae - Tetracycline (Eg: Doxycycline)

▪️Drug of choice for tropical sprue - Tetracycline

▪️Drug of choice for relapsing fever - Tetracycline

▪️Drug of choice for rocky spotted mountain fever - Tetracycline

▪️Drug of choice for tick typhus - Tetracycline

▪️Drug of choice for scrubs typhus - Tetracycline

▪️Drug of choice for syphilis - Penicillin G

▪️Drug of choice for toxoplasmosis - Cotrimoxazole

▪️Drug of choice for legionella - Azithromycin or Levofloxacin

▪️Drug of choice for lymphogranuloma venereum (LGV) - Azithromycin

▪️Drug of choice for kala-azar - Sodium Stibogluconate

▪️Oral drug of choice for kala-azar - Miltefosine

▪️Drug of choice for plague - Streptomycin

▪️Drug of choice for brucella - Streptomycin

▪️Drug of choice for tularemia - Streptomycin

▪️Drug of choice for rhinoscleroma - Streptomycin

▪️Drug of choice for actinomycosis - Penicillin-G

▪️Drug of choice for leprosy - Dapsone

▪️The most effective drug against Mycobacterium leprae - Rifampicin

▪️Drug of choice for herpes zoster - Valaciclovir

▪️Drug of choice for herpes simplex - Acyclovir

▪️Drug of choice for influenza - Oseltamivir

▪️Drug of choice for blood fluke - Praziquantel

▪️Drug of choice for lung fluke - Praziquantel

▪️Drug of choice for typhoid (Enteric fever) - I.V Ceftriaxone

▪️Drug of choice for leptospirosis - Penicillins

▪️Drug of choice for Plasmodium vivax - Chloroquine

▪️Drug of choice for Plasmodium falciparum - Artemisinin combination therapy (Artesunate + Pyrimethamine + Sulfadoxine)

▪️Drug of choice for cerebral malaria - Artesunate

▪️Drug of choice for malaria - Chloroquine

▪️Drug of choice for chloroquine-resistant malaria - Artemisinin combination therapy (Artesunate + Pyrimethamine + Sulfadoxine) - Streptomycin with doxycycline

▪️Drug of choice for brucella

▪️Drug of choice for candida - Fluconazole

▪️Drug of choice for aspergillosis - Voriconazole

▪️Drug of choice for dermatophytosis- Topically (Azole), Systemic (Griseofulvin)

▪️Drug of choice for Chagas disease - Nifurtimox, Benznidazole

▪️Drug of choice for dysuria - Phenazopyridine

▪️Drug of choice for gonorrhea - Procaine Penicillin

▪️Drug of choice for syphilis - Procaine penicillin

▪️Drug of choice for rickettsial infection - Tetracycline

▪️Drug of choice for plague - Tetracycline

▪️Drug of choice for anthrax - Doxycycline

▪️Drug of choice for toxoplasmosis - Trimethoprim Sulphamethoxazole

▪️Drug of choice for Haemophilus influenza type B - Rifampicin

▪️Drug of choice for prophylaxis of tuberculosis - Isoniazid

▪️Drug of choice for diarrhea in HIV patient - Octreotide

▪️Drug of choice for acyclovir-resistant herpes - Foscarnet

▪️Drug of choice for hepatitis B - Limuvidine

▪️Drug of choice for hepatitis C - Ribavarine & Interferon 2 alpha

▪️Drug of choice for lava migrans - Albendazole

▪️Drug of choice for inflammatory - Sulphasalazine

▪️Drug of choice for prophylaxis of newborn to TB mother- INH

▪️Drug of choice for accidental exposure of HIV to health care workers-Zidovudine with Lamivudine

▪️Drug of choice for salmonella - Ceftriaxone

▪️Drug of choice for meningitis - Ceftriaxone

▪️Drug of choice for gonorrhea - Ceftriaxone

▪️Drug of choice for resistant pneumococcal infections - Ceftriaxone Second line drug of choice for filariasis - Ivermectin

▪️Drug of choice for tapeworm infestation - Praziquantel

▪️Drug of choice for strongyloidiasis (Threadworm) - Ivermectin

▪️Drug of choice for onchocerciasis (River Blindness) - Ivermectin

▪️Drug of choice for tetanus - Metronidazole

▪️Drug of choice for listeria Ampicillin

▪️Second line drug of choice for listeria - SMZ -TMP (Sulphamethoxazole, Trimethoprim)

▪️Drug of choice for MRSA - Vancomycin

▪️Drug of choice for vancomycin-resistant staph aureus (VRSA) - Linezolid

▪️Drug of choice for neonatal meningitis - Ampicillin + 3rd generation Cephalosporin

▪️Drug of choice for bacteriosides fragialis - Clindamycin

▪️Drug of choice for pseudomembranous colitis - Metronidazole

▪️Drug of choice for amebiasis - Metronidazole Drug of choice for trench mouth - Metronidazole

▪️Drug of choice for bacterial vaginosis - Metronidazole

▪️Drug of choice for amoebic liver disease - Metronidazole

▪️Drug of choice for trichomoniasis - Metronidazole

▪️Drug of choice for giardiasis - Metronidazole

▪️Drug of choice for extraluminal amebiasis - Metronidazole Drug of choice for antibiotic-induced colitis - Metronidazole

▪️Drug of choice for anaerobic infections - Metronidazole Drug of choice for gonorrhea - Ceftriaxone

▪️Drug of choice for H.pylori eadication - Metronidazole

▪️Drug of choice for whooping cough - Erythromycin

▪️Drug of choice for cat scratch disease - Erythromycin

▪️Drug of choice for campylobacter infections - Erythromycin

▪️Drug of choice for gonococcal urethritis - Azithromycin

▪️Drug of choice for chancroid - Azithromycin

▪️Drug of choice for legionellosis - Azithromycin

▪️Drug of choice for trachoma - Azithromycin

▪️Drug of choice for inflammed acne - Minocycline

▪️Drug of choice for cystic acne - Isotretinoin

▪️Drug of choice for urinary tract infection - Norfloxacin

▪️Drug of choice for scabies - Permethrin

▪️Oral drug of choice for scabies - Ivermectin

▪️Drug of choice for filariasis - Diethyl Carbamazine (DEC)

▪️Drug of choice for listeria monocytogenes - Ampicillin

▪️Drug of choice for enterococcus fecalis - Ampicillin

▪️Drug of choice for toxoplasmosis - Cotrimoxazole

▪️Drug of choice for toxoplasmosis in pregnancy - Spiramycin

▪️Drug of choice for schistosomiasis - Praziquantel

▪️Drug of choice for leishmaniasis - Amphotericin B

▪️Drug of choice for Aspergillosis - Amphotericin B

▪️Drug of choice for roundworm (Ascaris) - Albendazole (Anti helminthic agent)

▪️Drug of choice for pinworm (Enterobius vermicularis) - Albendazole (Antihelminthic agent)

▪️Drug of choice for hookworm - Albendazole (Anti helminthic agent)

▪️Drug of choice for whip worm - Albendazole (Anti helminthic agent)

▪️Drug of choice for trichinae worm (Trichinella spiralis) - Albendazole (Antihelminthic agent)

▪️Drug of choice for guinea worm (Dracunculus medinensis) - Albendazole (Anti helminthic agent)

▪️Drug of choice for hydatid disease - Albendazole

▪️Drug of choice for filarial worm - Ivermectin (Anti helminthic agent)

▪️Drug of choice for threadworm (Strongyloides stercoralis) - Ivermectin (Antihelminthic agent)

▪️Drug of choice for pork tapeworm (Taenia solium) - Praziquantel

▪️Drug of choice for beef tapeworm (Taenia saginata) - Praziquantel

▪️Drug of choice for fish tapeworm (Diphyllobothrium latum) - Praziquantel

▪️Drug of choice for dog tapeworm (Echinococcus granulosus) - Praziquantel

▪️Drug of choice for dwarf tapeworm (Hymenolepis nana) - Praziquantel

▪️Drug of choice for liver fluke (Fasciola hepatica) - Triclabendazole

▪️Drug of choice for blood fluke - Praziquantel

▪️Drug of choice for lung fluke - Praziquantel

▪️Drug of choice for community acquired pneumonia - Clarithromycin

▪️Drug of choice for surgical prophylaxis - Cefazolin

▪️Drug of choice for pneumocystis carnii - Cotrimoxazole

▪️Drug of choice for cholera in children - Cotrimoxazole

▪️Drug of choice for filarial worm-Di-Ethyl Carbamazepine

▪️Drug of choice for Platyhelminthes - Praziquantel

▪️Drug of choice for trichomoniasis - Metronidazole

▪️Drug of choice for extended spectrum bacterial lactamase - Carbapenem

▪️Drug of choice for otitis media - Amoxicillin

▪️Drug of choice for Nocardia - Sulfonamides

▪️Drug of choice for neurosyphilis - Aqueous penicillin

▪️Drug of choice for donovanosis - Azithromycin or Doxycycline

▪️Drug of choice for Neisseria - Ceftriaxone

▪️Drug of choice for Cryptococcus - For induction( Amphotericin), for maintenance (Fluconazole)

▪️Drug of choice for Neurocysticercosis - Albendazole

▪️Drug of choice for typhoid (Enteric fever) - LV Ceftriaxone

▪️First line drugs for tuberculosis - Rifampicin, Isoniazid, Pyrazinamide, Ethambutol, Streptomycin (RIPES)

▪️Drug of choice for tuberculosis in renal failure - Rifampicin

▪️Drug of choice for prevention of tuberculosis in susceptible individuals - INH

▪️Drug of choice for treatment of tuberculosis in HIV positive patients taking protease inhibitor - Rifabutin

▪️Drug of choice for MDR strains of tuberculosis - Amikacin

▪️Drug of choice for latent tuberculosis - INH

▪️Drug of choice for INH resistant patients of latent tuberculosis - Rifampin

▪️Drug of choice for leprosy - Rifampin

▪️Drug of choice for lepra 1 reaction - Glucocorticoids

▪️Drug of choice for lepra 2 reaction - Glucocorticoids

▪️ Treatment of choice for multibacillary leprosy - Rifampin with Dapsone & Clofazamine

▪️Drug of choice for hot water born tuberculosis in hospital (M.xenopi)-Clarithromycin

▪️Drug of choice for cutaneous TB caused by atypical mycobacteria - Clarithromycin.

▪️Drug of choice for meningococcal prophylaxis - Ciprofloxacin

▪️Drug of choice for meningococcemia - Ceftriaxone

▪️Drug of choice for post spleenectomy sepsis - Ceftriaxone

Tuesday, 2 May 2023

Facts About the Muscular System.

Facts About the Muscular System.

The muscular system is what allows your body to move. Muscles are necessary for little movements, like smiling, and for big movements, such as running or throwing.

Some muscles you control, like your bicep when you’re lifting something heavy. Other muscles, such as those that help you breathe, move without you thinking at all.

In addition to being responsible for movement, the muscular system is also what keeps your body in whatever position it’s in against the pull of gravity.

1. Muscles are divided into three types: smooth, cardiac, and skeletal

▪️Smooth muscles are the involuntary muscles in your gut, blood vessels, and elsewhere that work without you consciously thinking about making them move.

▪️Cardiac muscles are in your heart.

▪️Skeletal muscles are attached to the bone and help you with everyday activities ranging from sitting and standing to walking, typing, and doing housework.

2. Your body contains more than 639 muscles

These include the muscles you can feel in your arms and legs, as well as muscles deep inside your body, like the one that keeps your heart beating and those that help you digest food. By comparison, your body has 206 skeletal bones.

3. Muscles are made up of special cells called muscle fibers

Their main quality is contractibility, which means the muscles can shorten or lengthen as needed. Almost all movement in your body happens because of muscle contractibility.

4. The largest muscle in the body is the gluteus maximus

It’s the main extensor muscle of the hip, though you may know it as the large muscle in the buttocks. It’s the largest muscle in the body because its main job is to support your trunk and maintain proper posture. The gluteus maximus is the main muscle used to help you walk upstairs.

5. The smallest muscles in the body are in your inner ear

They include the tensor tympani and the stapedius. They connect to your eardrum and hold your inner ear together. The smallest bones in the body are also in your ear.

6. The strongest muscle, based on its size, is the masseter

It’s a muscle in your jaw. It can close your teeth with a force as great as 200 pounds on your molars.

7. Muscles are attached to bones by tendons

Understanding the difference between tendons and ligaments can be confusing. In addition to attaching muscles to bones, tendons can also attach muscles to parts of your body such as your eyeballs. Ligaments connect one bone to another in your joints.

8. Muscles make up about 40 percent of your total body weight

9. The hardest working muscle in the body is the heart

On an average day, it pumps about 2,500 gallons of blood.

10. Some of your busiest muscles are those controlling eye movements

These muscles are constantly making adjustments as you read, watch TV, or look around you. In an hour of reading, your eyes may make as many as 10,000 coordinated movements.

11. Most of the heat produced in your body comes from muscle contraction

Muscle movement counts for almost 85 percent of the total heatTrusted Source produced inside the body. When you’re cold, your muscles contract involuntarily. When you shiver, those are muscles trying to warm your body.

12. The motor cortex on one side of your brain controls muscle movement on the other side of the body

The motor cortex on the right side of your brain controls the muscles on the left side of the body, while the motor cortex on the left side controls the muscles on your right side.

The brain sends movement signals through the spinal cord and out through the peripheral nervous system in your muscles.

The messages from the brain become more complex when there are more muscles involved in an activity, such as shooting a jump shot in basketball.

13. Muscles usually work in pairs

When one shortens, its corresponding muscle lengthens. Think about doing bicep curls. When you curl your arm up so the bicep is shorter, the tricep on the other side of your arm is straightened out.

14. Muscles can’t push.

They can only pull. When you’re pushing a door open, for instance, your muscles are actually pulling your elbow and shoulder against the door.

No matter what you’re doing, you have muscles at work. But to keep them healthy, they need exercise. Even your heart needs a workout to stay strong, which is why aerobic exercise that gets your heart rate up is so important.

The muscles in your arms, legs and elsewhere need exercise, too. As you age, you start to lose muscle mass. But if you exercise your muscles with strength training and resistance exercises, you can slow down that process and maintain a mighty muscular system for a long time. And that’s a fact.


ANTICANCER DRUGS


DRUG OF CHOICE SERIES
ANTICANCER DRUGS

▪️Drug of choice for breast cancer - Tamoxifen

▪️Drug of choice for glioma - Nitrosourea

▪️Drug of choice for colorectal cancer - 5 Fluorouracil

▪️Drug of choice for choriocarcinoma - Methotrexate

▪️Drug of choice for pancreatic carcinoma - Gemcitabine

▪️First line chemotherapy for cervix carcinoma - Cisplatin

▪️Drug of choice for the brain tumor - Lomustine

▪️Drug of choice for prostate carcinoma - Flutamide

▪️Drug of choice for insulinoma - Streptozotocin

▪️Drug of choice for polycythemia vera - Busulphan or Chlorambucil

▪️Drug of choice for carcinoma of endometrium - Progestins

▪️Drug of choice for kaposi sarcome - IF2 alpha

▪️Drug of choice for CLL - Chlorambucil or Fludarabine

▪️Drug of choice for acute myelocytic leukemia - Cytarabine with Mitoxantrone

▪️Drug of choice for wilm's tumor - Vincristine with Danctinomycin

▪️Drug of choice for acute promyeloblastic leukemia - Retinoic acid

▪️Drug of choice for hairy cell leukemia - Cladarabine

▪️Drug of choice for thyroid carcinoma-1-131 with Doxarubicin and cisplatin

▪️Drug of choice for stomach cancer - Fluorouracil with Cisplatin

▪️Drug of choice for CML-Imatinib or Busulfan

▪️Drug of choice for acute lymphocytic leukemia (ALL) - Vincristine +Prednisolone +Mercaptopurine + Cyclophosphamide +Methotrexate

▪️Drug of choice for ovarian cancer - Cisplatin with Paclitaxel

▪️Drug of choice for lung cancer - Cisplatin with Taxane

▪️Drug of choice for malignant melanoma - Dacarbazine

▪️Drug of choice for testicular cancer - Bleomycin+ Etoposide + Cisplatin

Monday, 1 May 2023

HEMATOLOGY

HEMATOLOGY

▪️Drug of choice for mierocytic anemia - Ferrous Sulfate

▪️Drug of choice for iron deficiency anemia in pregnancy - Ferrous sulphate

▪️Drug of choice for warfarin overdose - Vitamin K 

▪️Drug of choice for heparin overdose - Protamine sulphate

▪️Drug of choice for hairy cell leukemia - Cladribine 

▪️Drug of choice for chronic lymphocytic leukemia - Fludarabine

▪️Drug of choice for chronic myeloid leukemia (CML) - Imatinib 

▪️Drug of choice for chemotherapy-induced anemia - Erythropoietin

▪️Drug of choice for anemia due to chronic kidney disease (CKD) - Erythropoietin

▪️drug of choice for autoimmune hemolytic anemia - Prednisolone 

▪️Drug of choice for transient ischemic attack (TIA) - Aspirin

▪️Drug of choice for multiple myeloma - Melphalan 

▪️Drug of choice for heparin-induced thrombocytopenia - Argatroban

▪️Drug of choice for chemotherapy-induced leukopenia - Sargramostim 

▪️Drug of choice for chemotherapy induced thrombocytopenia - Oprelvekin

▪️First line drugs for multiple myeloma - Prednisolone, Prednisolone, Cyclophosphamide

▪️Drug of choice for heparin-induced thrombocytopenia - Argatroban

▪️Drug of choice for bleeding due to heparin - Hirudin 

▪️Drug of choice for warfarin overdose - Vitamin K

▪️Drug of choice for heparin overdose - Protamine 

▪️Thrombolytic agent of choice in acute myocardial infarction - Streptokinase 

▪️Drug of choice for arterial fibrillation induced clotting - Warfarin

▪️Drug of choice for prevention of stroke - Aspirin 

▪️Drug of choice for prevention of deep vein thrombosis - Low molecular weight heparin (LMWH)

▪️Drug of choice for preventing bleeding due to thrombolytic therapy-Epsilion amino capronic acid 

▪️Drug of choice for treatment of deep vein thrombosis - Low molecular weight heparin (LMWH)

▪️Drug of choice for pulmonary embolism - Low molecular weight heparin (LMWH)

▪️Drug of choice for anemia in chronic renal failure - Erythropoietin

Saturday, 29 April 2023

DRUG OF CHOICE SERIES1. CENTRAL NERVOUS SYSTEM

DRUG OF CHOICE SERIES

1. CENTRAL NERVOUS SYSTEM

▪️Drug of choice for generalized absent seizure -Ethosuximide and Sodium valproate

▪️Drug of choice for absence (Petit mal) seizures - Valproate

▪️Drug of choice for absence seizures in children - Ethosuximide

▪️Drug of choice for myoclonic seizures in men - Sodium Valproate

▪️Drug of choice for myoclonic seizures in women - Lamotrigine

▪️Drug of choice for focal seizure - Lamotrigine

▪️Drug of choice for generalized tonic-clonic seizures (GTCS) - Lamotrigine

▪️Drug of choice for tonic-clonic seizures - Sodium Valproate

▪️Drug of choice for infantile seizures - ACTH

▪️Drug of choice for rhinorrohea - Citrizine

▪️Drug of choice for phobias - SSRI's

▪️Drug of choice for reducing preanesthetic anxiety - Lorazepam

▪️Drug of choice for status epilepticus - I.V Lorazepam

▪️Drug of choice for febrile seizures - Diazepam

▪️Drug of choice for partial seizures - Carbamazepine

▪️Drug of choice for attention deficit hyperactivity disorder- Methylphenidate

▪️Drug of choice for Alzheimer's disease - Rivastigmine

▪️Drug of choice for obsessive-compulsive disorder (OCD) - Fluoxetine

▪️Drug of choice for drug-induced parkinsonism - Benzhexol

▪️Drug of choice for parkinsonism - Ropinirole, Pramipexole

▪️Drug of choice for glioma - Nitrosourea

▪️Drug which has pain relief properties without opioid disadvantages - Tramadol

▪️Drug of choice for sedation in patients with severe liver failure - Lorazepam

▪️Drug of choice for maintenance treatment of generalized anxiety disorder-Buspirone

▪️Drug of choice for febrile seizures - Diazepam

▪️Drug of choice for endoscopic and colonscopy - Midazolam

▪️Drug of choice for hypnosis in elderly - Zolpidem

▪️Drug of choice for diabetic neuropathy - Topiramate

▪️Drug of choice for neuropathic pain - Lamotrigine or Topiramate or Gabapentin

▪️Drug of choice for reducing alcohol craving - Naltrexone

▪️Drug for decreasing relapse of alcoholism - Acamprosate (NMDA receptor antagonist) or Naltrexone

▪️Drug of choice for alcohol detoxification - Disulfiram

▪️Drug of choice for smoking cessation - Bupropion

▪️Drug of choice for depression in parkinson disease - SSRI's

▪️Drug of choice for parkinson disease - Levodopa

▪️Drug of choice for psycosis in parkinson disease - Clozapine

▪️Drug of choice for depression - SSRI's

▪️Drug of choice for restless leg syndrome - Ropinirole

▪️Drug of choice for violent behaviour - Haloperidol

▪️Drug of choice for psychotic depression - Loxapine

▪️Drug of choice for neutropenia in felty's syndrome- Lithium

▪️Drug of choice for patients with extra pyramidal symptoms (EPS) - Clozapine

▪️Drug of choice for negative symptoms - Clozapine

▪️Drug of choice for treatment resistant schizophrenia - Clozapine

▪️Drug of choice for elderly with schizophrenia - Clozapine

▪️Drug of choice for peripheral neuropathy - Lamotrigine

▪️Drug of choice for bulimia - SSRI's (Eg: Fluoxetine)

▪️Drug of choice for acute mania - Lithium

▪️Drug of choice for serotonin syndrome - Cyproheptadine

▪️Drug of choice for nocturnal enuresis - Desmopressin

▪️Drug of choice for major depression - SSRI's

▪️Drug of choice for heat stroke - Chlorpromazine

▪️Drug of choice for OCD - SSRI's or Clomipramine

▪️Drug of choice for sleep walking - Carbamazepine

▪️Drug of choice for cluster headache - Lithium

▪️Drug of choice for cyclical vomiting - Lithium

▪️Drug of choice for bipolar mood disorder - Lithium

▪️Drug of choice for cerebral edema - Mannitol

▪️Drug of choice for increased intracranial pressure - Mannitol

▪️Drug of choice for psychomotor seizures - Carbamazepine

▪️Drug of choice for mania - Lithium Carbonate

▪️Drug of choice for Huntington chorea - Tetrabenazine

▪️Drug of choice for Parkinsonism - Ropinirole and Pramipexole

▪️Drug of choice for morning sickness - Hyoscine

▪️Drug of choice for multiple sclerosis - Amitriptyline

▪️Drug of choice for acute attack of migraine - Sumatriptan /Ergotamine Drug of choice for night terrors - Benzodiazepines

▪️Drug of choice for atypical depression - MAO inhibitors

▪️Drug of choice for hydrocephalus - Glycerol or Acetazolamide

▪️Drug of choice for cluster headache - Sumatriptan Treatment of choice for cluster headache - High flow 02

▪️Drug of choice for infantile spasm - ACTH

▪️Drug of choice for Huntington chorea - Tetra benzene

▪️Drug of choice for multiple sclerosis - Interferon B

▪️Drug of choice for pulmonary edema - Morphine

▪️Drug of choice generalized anxiety disorders - Diazepam (Benzodiazepines)

▪️Drug of choice for pain in terminal illness - Morphine

▪️Drug of choice for pain of acute myocardial infarction - Morphine

▪️Drug of choice for chronic cancer pain - Morphine

▪️Drug of choice for borderline personality disorder - Buspirone (5 HT partial agonist)

▪️Drug of choice for neonate with respiratory depression due to use of morphine to control severe labour pain - Naloxone

▪️Drug of choice for sedation in liver failure patients - Lorazepam

▪️Drug of choice for decreasing anxiety in children preoperatively- Antihistaminics

▪️Drug of choice for sedation in patients with porphyrias - Benzodiazepines

▪️Drug of choice for trigeminal neuralgia - Carbamazepine

▪️Drug of choice for status absence - Benzodiazepines

▪️Drug of choice for convulsion in lidocaine treated patients - Diazepam

▪️Drug of choice for tardive dyskinesia - Diazepam

▪️Drug of choice for convulsion in tetanus patients - Diazepam

▪️Drug of choice for delirium caused by ketamine - Diazepam

Drug of choice▪️DERMATOLOGY

Drug of choice DERMATOLOGY ▪️Drug of choice for taenia - Topical azoles (Eg: clotriamazole) ▪️Drug of choice for erythrodermic psoriasis ...